Patient Care

Methoxy Polyethylene Glycol-epoetin Beta (Mircera®) 

2026/07/09
What is this medication for?
Mircera® helps to increase red blood cell production in patients with anaemia that is related to kidney problems.
How should I take/use this medication?
  • Mircera® can be administered under the skin or into the veins. Use exactly as how your healthcare professional has told you.
  • Do not stop your medication without checking with your healthcare professional.

For injections under the skin:

StepsDescription
 How to prepare the injection Wash your hands thoroughly. 
Check the dosage strength of the injection and ensure that you are using the correct strength. Check the expiry date and ensure it has not expired.  


Allow Mircera to sit in room temperature for around 30 minutes for it to reach room temperature before injection  
Open and remove the plastic packaging containing the syringe. Peel off the protective seal from the plastic packaging. Hold the syringe by the device body. Do not touch the plunger or release clips yet.

Refer to Reference A below.
Inspect the solution inside: check that the solution is clear, colourless to slightly yellowish and does not contain any particles, avoid shaking the syringe. Pick up the needle cap, break the seal on the bottom of the needle using a twisting motion and remove the seal. Do not remove the needle from the cap, refer to Reference B below.

Hold onto the grey protective seal/cap covering the tip of the syringe and remove it by firmly bending and pulling it from the syringe. Refer to Reference C below.

Attach the needle with the needle cap firmly onto the syringe, refer to reference D below. Remove the needle cap from the needle. Refer to reference E below.

Wipe the injection site with an alcohol swab to disinfect the area. Leave it to dry for around 10 seconds. Do not discard the alcohol swab as it can be used later. Possible sites of injection include the stomach, thigh, upper arms or buttocks. Do not inject into the skin that is irritated, bruised, scarred, moles or has stretch marks. You should rotate the injection site within the same area to prevent your body from forming lipodystrophy (a small dent or lump in the skin that forms when a person repeatedly injects into the same spot). 
 Use your thumb and index finger to create a skin fold at the site of injection.
Insert the needle into the skin fold at a right angle. Once the needle is inserted, release the skin fold and press down the plunger slowly until all the solution has been injected. Do not release the plunger before the end of the injection. Needle guard (spring-like device in Reference F below) will not activate until the entire dose has been given will not activate until the entire dose has been given.

When the injection is completed, remove the needle from the skin without releasing your thumb from the plunger. Release the plunger after removing the needle from your skin.

Refer to Reference F below. 

Place the alcohol swab over injection site. Apply light pressure on the site for a few seconds. Do not rub or massage the injection site. 
How to discardReplace the needle cap and discard the entire syringe with the used needle in a puncture proof container, such as a plastic bottle with cap or cover. 
What should I do if i forget to take/use this medication?
If you forget to take a dose, take it as soon as you remember, and continue subsequent doses at the prescribed frequency. If it is close to the time for your next dose, skip the missed dose and go back to your usual timing. Do not take two doses at the same time to make up for the missed dose.

Disclaimer:

  • Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.
  • If you take more than the recommended dose, please seek medical advice immediately.
  • The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

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