Patient Care

Oxymetazoline Nasal Drop 

2025/07/23
What is this medication for?
Oxymetazoline is used to relief nasal congestion. 
How should I take/use this medication?

Oxymetazoline nasal drops should only be used for short periods of time (maximum consecutively for 5-7 days). A treatment-free period should precede any repeated use to minimize risk of rebound nasal congestion. 

Administering the medication

StepsDescription
 1 Blow your nose gently.
2Check the dropper tip to make sure that it is not chipped or cracked. Avoid touching the dropper tip against your clean nose. 
3Tilt your head as far back as possible, or lie down on your back on a flat surface (such as a bed) and hang your head over the edge.
4Place the correct number of drops into your nose.
5Remain in this position for a few minutes.
6Clean the dropper tip with warm water. Cap the bottle right away.
 

Oxymetazoline Nasal Drop steps 1 to 5

What precautions should I take?

Inform your healthcare professional if:

  • You are allergic to oxymetazoline or any of the excipients in the nasal drop.
    • You are pregnant, planning to become pregnant, or breastfeeding.
    • You are on monoamine oxidase inhibitor (i.e. selegiline)
    • Increase intraocular pressure, especially narrow-angle glaucoma
    • You have poorly controlled cardiovascular disease (e.g. Coronary heart disease, hypertension) or metabolic disease (i.e. hyperthyroidism, diabetes) or hyperplasia of prostate
    • You have a medical history of pheochromocytoma
What are some common side-effects of this medication?
  • Occasionally, burning or dryness of the nasal mucosa and sneezing. In rare cases- after the effect has worn off- an intense sensation of “blocked” nose (reactive hyperaemia) and nosebleed (epistaxis).
  • Overuse of oxymetazoline nasal drops may lead to systemic sympathomimetic effects like palpitations, accelerated pulse (tachycardia) and increase in blood pressure
What are some rare but serious side-effects that I need to seek medical advice immediately?

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

How should I store this medication?

Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.

Discard 6 months after opening.

How should I throw away this medication safely?
Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Disclaimers 
Please take note that the above is not a complete list of all possible side effects. If you  have any concerns about your medication or if you have other side effects that you think  are caused by this medication, please consult your doctor or pharmacist. If you take more than the recommended dose, please seek medical advice immediately.  The information provided on this page does not replace information from your healthcare  professional. Please consult your healthcare professional for more information.

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