Patient Care

Diphenhydramine Cough Expectorant

2025/07/23
What is this medication for?
Cough expectorants are a group of medications that works by thinning and loosening mucus in the airways, helping to clear chest congestion thus making breathing easier. 
How should I take/use this medication?
  • Take these medications as recommended by your healthcare professional. Consult your healthcare professional if you are not sure how to take these medications correctly.
  • Shake the bottle well before use.
  • If your symptoms persist or worsen after one week of taking these medications, please talk to your healthcare professional.
What should I do if I forget to take/use this medication?
Cough expectorants may be taken when required for a short period of time. This means that you do not have to take them if you do not have any symptoms. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue normally. Do not take two doses or extra medication to make up for the missed dose.
What precautions should I take?

Inform your healthcare professional if:

  • You are allergic to expectorants, or any other ingredients used in these medications.
  • You are taking any other medications, including supplements, traditional medications and herbal remedies.
  • You have existing conditions such as gastric ulcers, liver or kidney problems and lung conditions e.g. Chronic Obstructive Lung Disease (COPD) or severe uncontrolled asthma.
  • You are pregnant, planning to become pregnant or breastfeeding.•You have a cough with thick yellow or green phlegm or mucus, or blood.
  • You have a fever of more than 38.6°C.
  • You lose weight even though you are not trying to do so.
  • You have night sweats.
  • Your cough lasts for more than 3-4 weeks.
  • You start having new symptoms during self-treatment.
What are some common side-effects of this medication?
  • Drowsiness or dizziness
    • Avoid driving, operating machinery or other activities which require concentration, if affected.
  • Common side effects may include nausea or vomiting, stomach upset and constipation.
    • These side effects are usually mild and will pass quickly.
What are some rare but serious side-effects that I need to seek medical advice immediately?

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop these medications and see your doctor immediately.

What food or medication should I avoid when I take or use this medication?
Let your healthcare professional know if you are taking, or planning to take any other herbal products, supplements or medications.
How should I store this medication?
Store in a cool and dry place away from direct sunlight. Keep these medications away from children.

For liquids, discard the bottle 6 months after first opening or if expired, whichever is sooner.
How should I throw away this medication safely?
Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Disclaimers
Please take note that the above is not a complete list of all possible side effects. If you  have any concerns about your medication or if you have other side effects that you think  are caused by this medication, please consult your doctor or pharmacist. If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

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