Research and diagnosis of risk group 3 (RG3) biological agents require specially designed biocontainment areas and operating procedures to ensure the safety of operators, researchers and communities. Established in November 2014 at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), the Biosafety Level-3 (BSL-3) Core Facility is the largest research-focused biocontainment facility in Singapore. The facility supports research and diagnostic work involving a range of RG3 pathogens. It is certified by the Biosafety Branch of the Singapore Ministry of Health and the Agri-Food & Veterinary Authority of Singapore.
Situated in the Centre for Translational Medicine (MD6) on the NUS Kent Ridge campus, the state-of-the-art 650 m2 space is equipped with both essential and complex laboratory equipment (including flow cytometers, spectrophotometers and an aerosolization machine for establishing infectious disease mouse models). Associate Professor Justin Chu Jang Hann serves as the head of the BSL-3 Core Facility, directing a team of skilled personnel who operate the facility as well as assist in performing in vitro and in vivo work with RG3 pathogens. Currently, the facility is regularly used by more than 40 researchers, from NUS and other institutions, to conduct their research on RG3 biological agents. It also supports National Public Health Laboratory activities such as RG3 pathogen surveillance and national preparedness for effective outbreak management.
Ms. Sindhu Ravindran (Senior Manager & Biosafety Coordinator)