
At NUHS, research strengthens the foundations of Appropriate and Value-Based Care (AVBC). It supports how we improve care, guide decisions and sustain impact in practice. To generate evidence that informs better care and better decisions, our research is shared through evaluations, conference presentations, and peer-reviewed publications. This contributes to the growing body of knowledge in valued-based healthcare in Singapore and globally.
Our work translates data into actionable insights. It supports care redesign, guides clinical and operational decisions, and advances understanding of how appropriate, patient-centred care creates value.
Award Winning Research
- Focused Accelerated Surgical Treatment for Total Knee Replacement (FAST-TKR) at MOH AVBC Conference 2025 (Top 3 Poster Presentation)
- Elective Percutaneous Coronary Intervention (PCI) Same Day Discharge Initiative at MOH AVBC Conference 2025 (Top 3 Oral Presentation)
- Value-Based Optimization of Door-to-Needle (DTN) Time in Stroke Care: Functional and Cost Benefits of Achieving a 30-Minute Target at NUHS Scientific & Innovation Summit 2024 (First Prize of Poster Presentation)
- The Value Impact of Robotic Hysterectomy in Gynecological Malignancy at ACE HTA VBHC Conference 2024 (Top 3 Oral Presentation)
- Impacts of Antimicrobial Stewardship Program (ASP) on Broad-Spectrum Prescription Reduction and Patient Outcomes at ACE HTA VBHC Conference 2024 (Top 10 Poster Presentation)
- Slowing increase in drug spending via data-driven practice change at ACE HTA VBHC Conference 2024 (Top 10 Poster Presentation)
- A whole-of-hospital Value Driven Outcomes approach to optimize clinical outcomes and minimize hospitalization for Sepsis (Winner of International Consortium for Health Outcomes Measurement (ICHOM) 2023, Top 3 Oral Presentation at ACE HTA VBHC Conference 2022)
- National University Hospital’s (Singapore) use of Value Driven Care methodology to improve patient outcomes at a sustainable cost in Total Knee Replacement Surgery through data-driven change to clinical practice (Top 5 Oral Presentation) at ICHOM 2023
- Optimizing Outcomes of Very Low Birth Weight Babies at ACE HTA VBHC Conference 2022 (Top 3 Oral Presentation)
- Superior Outcomes In Total Knee Replacement Value Driven Outcomes Project at HTA VBHC Conference 2022 (Top 3 Poster Presentation)
- NUHS THR Value Driven Outcomes (VDO) Superior Outcomes in Total Hip Replacements at HTA VBHC Conference 2022 (Top 8 Oral Presentation)
Peer-Reviewed Journal Publications
- Merchant, R.A., Dong, Y.Q., Kumari, S. and Murphy, D., 2025. Frailty, malnutrition, healthcare utilization, and mortality in patients with dementia and cognitive impairment obtained from hospital administrative data. Frontiers in Medicine, 12, p.1540050.
- Wang, J.D.J., Dong, Y.Q., Yeo, J.Y., Teo, K.S.H., Ng, S., Jing, M., Chan, B.P., Yeo, L.L., Chia, M.L., Widjaja, L. and Wong, L.Y., 2025. Improved functional outcomes and cost benefits of door-to-needle time under 30 min in acute ischemic stroke: an observational study. Frontiers in Stroke, 4, p.1583875.
- Loh, B.J.S., Teo, L.S., Kumari, S., Santoso, E.G. and Murphy, D., 2025. Value-Driven Care Methodology in Total Knee Replacement Surgery in Singapore. NEJM Catalyst Innovations in Care Delivery, 6(4), pp.CAT-24.
- Wang, Z., Dong, Y.Q., Kumari, S., Murphy, D. and Merchant, R.A., 2025. The Impact of Frailty, Activity of Daily Living, and Malnutrition on Mortality in Older Adults with Cognitive Impairment and Dementia. Nutrients, 17(16), p.2612.
- See, K.C., Murphy, D.P., Kumari, S., Santoso, E.G. and Kuan, W.S., 2023. A Whole-of-Hospital Value-Driven Outcomes Approach to Optimize Clinical Outcomes and Minimize Hospitalization for Community-Acquired Sepsis. NEJM Catalyst Innovations in Care Delivery, 4(7), pp.CAT-23.
- Lim, Z., Ling, N., Ho, V.W.T., Vidhya, N., Chen, M.Z., Wong, B.L.L., Ng, S.E., Murphy, D. and Merchant, R.A., 2023. Delirium is significantly associated with hospital frailty risk score derived from administrative data. International Journal of Geriatric Psychiatry, 38(1), p.e5872.
- Tan, L., Lim, J., Lee, J., Loo, L., Lomanto, D., Parameswaran, R., Shabbir, A., Murphy, D., Kumari, S. and Wijerathne, S., 2023. The impact of value-driven outcomes initiative on endo-laparoscopic groin hernia repair. Hernia, 27(5), pp.1299-1306.
- Wong, B.L.L., Chan, Y.H., O’Neill, G.K., Murphy, D. and Merchant, R.A., 2023. Frailty, length of stay and cost in hip fracture patients. Osteoporosis International, 34(1), pp.59-68.
- Merchant, R.A., Ho, V.W.T., Chen, M.Z., Wong, B.L.L., Lim, Z., Chan, Y.H., Ling, N., Ng, S.E., Santosa, A., Murphy, D. and Vathsala, A., 2022. Outcomes of care by geriatricians and non-geriatricians in an academic hospital. Frontiers in Medicine, 9, p.908100.
Selected Oral/Poster Presentations
- Impacts of Antimicrobial Stewardship Program on Broad-Spectrum Prescription Reduction and Patient Outcomes at BMJ International Forum on Quality and Safety in Healthcare
- Antimicrobial Stewardship Program Value Driven Outcomes at European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
- “ULTrA (Urate Lowering Therapy to Acute Treatment ratio)” Index – Proposed Quality Index to Decrease Preventable Healthcare Burden of Gout at Asia-Pacific League of Associations for Rheumatology Congress (APLAR)
- Integrated General Hospital – A patient-centric approach to managing multimorbidity at VBHC Prize
- Streamlining Cardiac Monitoring for Atrial Fibrillation Detection in Ischemic Stroke Patients at VBHC Prize
- Optimizing Door-to-Needle (DTN) Time in Stroke Care: Functional and Cost Benefits of Achieving a 30-Minute Target at World Stroke Congress
- Slowing increase in drug spending via data-driven practice change at ACE HTA VBHC Conference
- The Value Impact of Robotic Hysterectomy in Gynecological Malignancy at ACE HTA VBHC Conference
- Streamlining Cardiac Monitoring for Atrial Fibrillation Detection in Ischemic Stroke Patients at ACE HTA VBHC Conference
- Impacts of Antimicrobial Stewardship Program (ASP) on Broad-Spectrum Prescription Reduction and Patient Outcomes at ACE HTA VBHC Conference
- The Integrated General Hospital: One Patient, One Bed, One Care Team, One Principal Doctor, and One with Community at International Consortium for Health Outcomes Measurement (ICHOM)
- Investigation on disparities of frailty and care utilization among older adults with dementia through a patient-level cluster-wide value-driven outcomes (VDO) project at International Consortium for Health Outcomes Measurement (ICHOM)
- Value-Based Optimization of Door-to-Needle (DTN) Time in Stroke Care: Functional and Cost Benefits of Achieving a 30-Minute Target at International Consortium for Health Outcomes Measurement (ICHOM), NUHS Scientific & Innovation Summit
- Investigation on disparities of frailty and care utilization among older adults with dementia through a patient-level cluster-wide value-driven outcomes (VDO) project at NUHS Scientific & Innovation Summit
- Impact of Robotic Minimally Invasive Hysterectomy (MIH) in Uterus Cancer at NUHS Scientific & Innovation Summit
- Frailty and Healthcare Utilization for Persons with Dementia and Cognitive Impairment Obtained from Administrative Data at European Geriatric Medicine Society (EuGMS) Congress
- Predicting frailty and clinical outcomes using cluster analysis on activities of daily living (ADL) scales for older adults with dementia and cognitive impairment at Imagine AI
- The economic trends of inpatient diabetic foot care – cost drivers and impact of high-cost users at HQSS
- The Economic Trends of Inpatient Diabetic Foot Care in a Multi-ethnic Asian Population – Cost Drivers and Impact of High-cost users at International Health Economics Association Congress
- A Person-Centric and Cluster-Wide Approach to Optimize Care for Persons with Dementia and Cognitive Impairment at VBHC Congress (Australia)
- Transforming Care Pathways: Advancing from Episodic Based to End-to-End Care at VBHC Congress (Australia)
- Appropriate Value-Based Healthcare in Integrated Discharge Program at VBHC Congress (Australia)
- Focused Accelerated Surgical Treatment for Total Knee Replacement (FAST-TKR) at VBHC Congress (Australia)
- Elective Percutaneous Coronary Intervention (PCI) Same Day Discharge Initiative at VBHC Congress (Australia), VBHC Prize
- Utilisation of a Value Driven Outcomes (VDO) Framework in Hospital-At-Home at World Hospital at Home Congress
- A Multidisciplinary Approach to Reduce Vancomycin-Associated Nephrotoxicity at BMJ International Forum on Quality and Safety in Healthcare
- Elective Percutaneous Coronary Intervention (PCI) Same Day Discharge Initiative at MOH AVBC Conference
- Integrated Discharge Program for End-to-End Patient Journey in National University Hospital at MOH AVBC Conference
- NUH Deprescribing and Medication Optimization Initiative: Embedding Deprescribing into Inpatient Care at MOH AVBC Conference
- Co-Designing NUHS’s ePROMs Strategy: Lessons from the Cluster Strategy Workshop at MOH AVBC Conference
- Optimising Ascitic Drainage Care: Implementing a Nurse-Led Short-Stay Pathway to Enhance Value and Reduce Cost at MOH AVBC Conference, International Consortium for Health Outcomes Measurement (ICHOM)
- Focused Accelerated Surgical Treatment for Total Knee Replacement (FAST-TKR) at MOH AVBC Conference
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