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Adj A/Prof William Kong Kok Fai

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  • Senior Consultant, Department of Cardiology, National University Heart Centre, Singapore
  • Adjunct Associate Professor, Yong Loo Lin School of Medicine, National University of Singapore


MBChB (NZ), FRACP (Australia), FRCP (Edin), FESC (EU), FACC (USA)



Clinical Disciplines/Programmes:

Adult Congenital, Cardiac Imaging (Echocardiography), Cardiology (Heart), General Cardiology, Heart Valve Disease, Hypertension, Lipid Disorders, Structural Heart Disease & Transcatheter Interventions

Special Interests:

Bicuspid Aortic Valve Disease, diabetes mellitus and lipid disorder, Hypertension, Infective Endocarditis, Interventional Transesophageal Echocardiography, Valvular Heart Disease

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Adj A/Prof William Kong Kok Fai graduated from the Auckland University, New Zealand with a Bachelor of Medicine and Bachelor of Surgery (MBChB) . He completed advanced specialist training in Cardiology in Christchurch Hospital and Wellington Hospital in New Zealand. He was admitted as a fellow of Royal Australasian College of Physician (FRACP) in Cardiology in 2011.

He obtained the Academic Medicine Development Award (AMDA) in 2014 to undergo subspecialty training in interventional echocardiography, structural heart disease/valvular heart disease in Leiden University Medical Centre in the Netherlands under the supervision of Dr Victoria Delgado and Professor Jeroen J Bax, the past president of European Society of Cardiology (ESC). He is also undergoing PhD study at the Leiden University Medical Centre (LUMC) at Leiden, the Netherlands examining the epidemiology, clinical, genetics and imaging aspects of bicuspid aortic valve and aortopathy.

He was subsequently elected Fellow of the Royal College of Physicians (Edinburgh), Fellow of the European Society of Cardiology in 2017, and Fellow of the American College of Cardiology in 2018. He was appointed as Specialty Editor in Cardiology for Singapore Medical Journal since 2016.

Currently, he is running a weekly Specialist Valve Clinic to follow up patients with valvular heart disease and to provide transesopahgeal echocardiography and stress echocardiography services in the National University Hospital (NUH). He is also a member of the Heart Team providing echocardiographic assessment/support for transcatheter therapies for patients who deemed high risk for surgery. In 2020, Adj A/Prof Kong has been appointed as the Clinical Director of Echocardiography & Non-invasive Diagnostic Cardiology, Department of Cardiology, National University Heart Centre, Singapore (NUHCS).

Adj A/Prof Kong has published as first author multiple times in some highest impact factor cardiology journals such as European Heart Journal, Journal of American College of Cardiology, Circulation: Cardiovascular Imaging and JAMA Cardiology. He is a reviewer for several international cardiology journals such as Circulation, European Heart Journal and Journal of American Society of Echocardiography (JASE).

He supervises research and clinical training for senior residents and clinical fellows from Singapore and overseas. Adjunct Associate Professor Kong is currently the primary investigator and clinical lead of multiple worldwide valvular and cardiomyopathies research.

Adj A/Prof Kong is also a clinician educator at the NUS Yong Loo Lin School of Medicine who is actively involved in training year 1-5 medical students. Adj A/Prof Kong' strong passion of educating the next generation of doctors and echo technicians enabled him to be nominated best tutor at the NUS Yong Loo Lin School of Medicine.

Journals & Publications

1. Kong WKF, Salsano A, Giacobbe DR, Popescu BA, Laroche C, Duval X, Schueler R, Moreo A, Colonna P, Piper C, Calvo-Iglesias F, Badano LP, Srdanovic I, Boutoille D, Huttin O, Stöhr E, Timóteo AT, Vaskelyte JJ, Sadeghpour A, Tornos P, Abid L, Poh KK, Habib G, Lancellotti P.
Outcomes of culture-negative vs. culture-positive infective endocarditis: the ESC-EORP EURO-ENDO registry. Eur Heart J. 2022 Jun 8:ehac307. doi: 10.1093/eurheartj/ehac307. (Impact factor 35.86)
2. Kong WKF, Vollema EM, Prevedello F, Perry R, Ng ACT, Poh KK, Almeida AG, González A, Shen M, Yeo TC, Shanks M, Popescu BA, Galian Gay L, FijaƂkowski M, Liang M, Chen RW, Ajmone Marsan N, Selvanayagam J, Pinto F, Zamorano JL, Pibarot P, Evangelista A, Delgado V, Bax JJ. Prognostic implications of left ventricular global longitudinal strain in patients with bicuspid aortic valve disease and preserved left ventricular ejection fraction. Eur Heart J Cardiovasc Imaging. 2020 Jul 1;21(7):759-767. doi: 10.1093/ehjci/jez252. (Impact factor 9.13)
3. Kong WKF, Bax JJ, Michelena HI, Delgado V.Sex differences in bicuspid aortic valve disease. Prog Cardiovasc Dis. 2020 Jul-Aug;63(4):452-456. doi: 10.1016/j.pcad.2020.06.004. Epub 2020 Jun 27. (Impact factor 11.28)
4. Kong WKF, Bax JJ, Delgado V. Left ventricular myocardial fibrosis: a marker of bad prognosis in symptomatic severe aortic stenosis. Eur Heart J. 2020 May 21;41(20):1915-1917. doi: 10.1093/eurheartj/ehaa151. (Impact factor 35.86)
5. Kong WK, Loh PH, Teo L, Ong CC, Wong RC. Takotsubo hypertrophic obstructive cardiomyopathy and bicuspid valvulopathy: implication of multiple imaging modalities. Eur Heart J. 2019 Jul 1;40(26):2172. doi: 10.1093/eurheartj/ehy673. (Impact factor 35.86)
6. Kong WKF, Choong CC, Sule JA, Poh KK, Kofidis T. Paravalvular root abscess with mycotic pseudoaneurysm. Eur Heart J. 2018 Nov 1;39(41):3751-3752. doi: 10.1093/eurheartj/ehy416. (Impact factor 35.86)
7. Kong WKF, Regeer MV, Poh KK, Yip JW, van Rosendael PJ, Yeo TC, Tay E, Kamperidis V, van der Velde ET, Mertens B, Ajmone Marsan N, Delgado V, Bax JJ. Inter-ethnic differences in valve morphology, valvular dysfunction, and aortopathy between Asian and European patients with bicuspid aortic valve. Eur Heart J. 2018 Apr 14;39(15):1308-1313. doi: 10.1093/eurheartj/ehx562. (Impact factor 35.86)
8. Kong WKF, Vollema EM, Katsanos S, Kamperidis V, van Rosendael PJ, van der Kley F, de Weger A, Ajmone Marsan N, Delgado V, Bax JJ. Transcatheter aortic valve thrombosis: the relation between hypo-attenuated leaflet thickening, abnormal valve haemodynamics, and stroke. Eur Heart J. 2017 Apr 21;38(16):1207-1217. doi: 10.1093/eurheartj/ehx031. (Impact factor 35.86)
9. Kong WK, Delgado V, Poh KK, Regeer MV, Ng AC, McCormack L, Yeo TC, Shanks M, Parent S, Enache R, Popescu BA, Liang M, Yip JW, Ma LC, Kamperidis V, van Rosendael PJ, van der Velde ET, Ajmone Marsan N, Bax JJ. Prognostic Implications of Raphe in Bicuspid Aortic Valve Anatomy. JAMA Cardiol. 2017 Mar 1;2(3):285-292. doi: 10.1001/jamacardio.2016.5228. (Impact factor 30.15)
10. Kong WK, Regeer MV, Ng AC, McCormack L, Poh KK, Yeo TC, Shanks M, Parent S, Enache R, Popescu BA, Yip JW, Ma L, Kamperidis V, van der Velde ET, Mertens B, Ajmone Marsan N, Delgado V, Bax JJ. Sex Differences in Phenotypes of Bicuspid Aortic Valve and Aortopathy: Insights From a Large Multicenter, International Registry. Circ Cardiovasc Imaging. 2017 Mar;10(3):e005155. doi: 10.1161/CIRCIMAGING.116.005155. (Impact factor 8.59)

Professional Memberships

  • Fellow of the Royal Australasian College of Physician (FRACP)
  • Fellow of European Society of Cardiology (FESC)
  • Fellow of Royal College of Physician (FRCP Edinburgh)
  • Fellow of America College of Cardiology (FACC)

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