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Sepsis

Sepsis Value-Driven Outcomes (VDO) in National University Hospital (NUH)

Case study


Background
  • Community-acquired sepsis incurs high morbidity and mortality
  • In 2019, there were 1,985 cases of sepsis in NUH, resulting in inpatient mortality rate of 13%
  • Sepsis VDO project launched in 2017

Objectives
Encourage continuous improvement of "Value of Care" through:

  • Increasing quality of care while reducing cost
  • Minimising variation in care delivered to patients


Methodology

​2017
Conceptualisation of Sepsis VDO (Emergency Department, Department of Medicine, Medical Informatics Team, Finance team), literature review, determined quality indicators and costs to be measured​
​2018
​Cascaded downstream by training of ground teams (simulation sessions)
​2019
​Sepsis management concepts and processes implemented and introduced to junior doctors during orientation
​2020
E​nhanced "Trigger Programme" initiative
​2021
​Reinforcement of key clinical concepts through intensive and remote education efforts; feedback loops with clinical departments

Sepsis-methodology

Quality Indicators

  • No inpatient mortality
  • No emergency readmissions ≤ 30 days (same cause)
  • Blood cultures (within 3 hours from triage)
  • Antibiotics (within 3 hours from triage)
  • Intravenous fluids (within 3 hours from triage)

Results
  • Increase in Clinical Quality Index (CQI) driven by decreasing cost and increasing quality
  • An absolute decrease of 12% points in mean total cost per patient from 2019 to 2021

  • Antibiotics administration within 3 hours of triage. Increase of 7% to 51% in 2021.
  • In 2021, 32% of patients experience Perfect Quality of Care compared to 25% in 2019. (Increase of 7%)
  • Rate of appropriate de-escalation of antibiotics. Increase of 1% to 95% in 2021 when compared to 2019
  • Average length of stay. Decrease of 3 days from 17 days in 2019 to 14 days in 2021.
  • Stable inpatient mortality between 11% and 13% (compares favourably to 18.3% in ANZ)


Conclusion
Improvements in CQI and minimising variation in care achieved and sustained without compromise in mortality, despite challenges posed during COVID-19 pandemic in 2020 and 2021.

 

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