Dr. Soon Yu Yang is a Senior Consultant in the Department of Radiation Oncology at the National University Cancer Institute in Singapore. He specializes in radiotherapy for lung cancer and brain metastases, particularly in stereotactic radiotherapy and the integration of radiotherapy with targeted therapies and immunotherapies. As a clinician-trialist, Dr. Soon's research focuses on precision radiotherapy. His aim is to determine who should receive radiotherapy, when it should be used alongside modern systemic treatments, and how it can be tailored to tumor biology. He co-led the OUTRUN trial, an international randomized study evaluating the use of osimertinib with or without stereotactic radiosurgery for patients with EGFR-mutated non-small cell lung cancer and brain metastases. OUTRUN also contributed to the STARLET joint analysis of two randomized trials. Additionally, he serves as Chair of the Lung Working Party for the Trans Tasman Radiation Oncology Group. Dr. Soon has published over 80 peer-reviewed articles. He holds a Master of Science in Clinical Epidemiology from Harvard University, a PhD in clinical trial methodology, and a Master of Biostatistics from the University of Sydney. His methodological interests include clinical trial design, causal inference, survival analysis, and evidence synthesis. He is a faculty member of the Australia and Asia-Pacific Clinical Oncology Research Development Workshop and the ASCO International Clinical Research Scholars Workshop, where he mentors early-career investigators in developing rigorous, clinically relevant research. His goal is to design and conduct high-quality clinical trials that lead to more personalized, effective, and less burdensome cancer treatments.
Selected Publications
