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2024/03/11
Doctor Detail

A/Prof Ng Kar Hui

Photo of A/Prof Ng Kar Hui

Designations:

  • Senior Consultant, Division of Paediatric Nephrology, Dialysis and Renal Transplantation, Department of Paediatrics, Khoo Teck Puat - National University Children's Medical Institute, National University Hospital
  • Senior Consultant, Division of Genetics and Metabolism, Department of Paediatrics, Khoo Teck Puat - National University Children's Medical Institute, National University Hospital
  • Senior Consultant, Paediatric Kidney Transplantation Programme, National University Centre for Organ Transplantation, National University Hospital
  • Associate Professor, Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore

Qualifications:

MBBS (S'pore), MMed (Paeds) (S'pore), MRCPCH (UK), FRCPCH (UK), FAMS (Paeds) (S’pore)

Specialties/Sub-specialties:

Paediatric Medicine

Clinical Disciplines/Programmes:

Organ Transplantation, Paediatric Kidney Transplantation Programme, Paediatric Nephrology, Dialysis & Renal Transplantation (Kidney, Bladder & Urine Conditions)

Biosketch

A/Prof Ng Kar Hui obtained her Master of Medicine (Paediatrics) and has been a fellow of the Royal College of Paediatrics and Child Health (UK). She is accredited as a specialist in Paediatric Medicine and Paediatric Nephrology by the Ministry of Health, Singapore. A/Prof Ng's clinical practice involves all areas of paediatric nephrology, including dialysis and kidney transplantation. She has an interest in genetic kidney disease as well as dialysis in young children. She sees patients in the Kidney Genetics Clinic as well as expectant couples in Fetal Kidney Clinic.

A/Prof Ng pursued a two-year research fellowship at Boston Children's Hospital after receiving a fellowship from the Singapore National Medical Research Council. Upon her return, she pioneered the research programme on the genetics of kidney diseases in Singapore, and started the collaborative network DRAGoN (Deciphering Diversities: Renal Asian Genetics Network) to study this across South Asia. She was the Principal Investigator for national competitive research grants including the Clinician Scientist Awards. She also founded and leads the Renal Alliance for PrecIsion Diagnosis in Singapore (RAPIDS) which comprises of a multi-institutional, multi-disciplinary network of kidney and genomics experts and aims to implement genomics medicine in kidney clinical practice. She is a Subject Editor for the Nephrology Journal and has published and reviewed many papers in her field in the medical literature.

In addition, she has written several book chapters and has been invited to lecture at various overseas medical congresses. Being an Education Ambassador in the International Society of Nephrology, she frequently travels to the less privileged communities in Asia to teach paediatric nephrology to doctors. A/Prof Ng also enjoys teaching paediatrics to medical students and young doctors and is a two-time recipient of the NUS Faculty Teaching Excellence Award.

She is currently a member in the Paediatric Medicine Resident Advisory Committee as well as the Clinical Ethics Committee in NUH. She also leads efforts in clinical implementation of genomics medicine in NUHS.

Awards

  • 2017 - Faculty Teaching Excellence Award for academic years 2015/2016, NUS
  • 2021 - Young Investigator Award, 14th Asian Congress of Pediatric Nephrology, Taiwan

Journals & Publications

  1. Gunasekara WD, Ng KH, Chan YH, Aragon E, Foong PP, Lau YW, . . . Yap HK (2010). Specialist pediatric dialysis nursing improves outcomes in children on chronic peritoneal dialysis. Pediatric Nephrology (Berlin, Germany), 25(10):2141-7. doi: 10.1007/s00467-010-1581-3
  2. Sathe KP, Yeo WS, Liu ID, Ekambaram S, Azar M, Yap HK, Ng KH (2015). Recurrent white thrombi formation in hemodialysis tubing: a case report. BMC Nephrology, 16:3. doi: 10.1186/1471-2369-16-3
  3. Sun ZJ, Ng KH, Liao P, Zhang Y, Ng JL, Liu ID, . . . Yap HK (2015). Genetic Interactions Between TRPC6 and NPHS1 Variants Affect Posttransplant Risk of Recurrent Focal Segmental Glomerulosclerosis. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 15(12):3229-38. doi: 10.1111/ajt.13378
  4. Chaturvedi S, Ng KH, Mammen C. The path to chronic kidney disease following acute kidney injury: a neonatal perspective. Pediatric Nephrology (Berlin, Germany), 32(2):227-241. doi: 10.1007/s00467-015-3298-9
  5. Chan CY, Ng KH, Chen J, Lu J, Lee CG, Tan PH, …Yap HK (2016). Novel role of Vav1-Rac1 pathway in actin cytoskeleton regulation in Interleukin-13-induced minimal change-like nephropathy. Clinical Science (London, England : 1979). doi:10.1042/CS20160312.
  6. Ng KH, Zhang SL, Tan HC, Kwek SS, Sessions OM, Chan CY, Liu ID, Lee CK, Tambyah PA, Ooi EE, Yap HK. Persistent Dengue Infection in an Immunosuppressed Patient Reveals the Roles of Humoral and Cellular Immune Responses in Virus Clearance. Cell Host Microbe. 2019 Nov 13;26(5):601-605.e3. doi: 10.1016/j.chom.2019.10.005. Epub 2019 Oct 29.
  7. Sharon Teo, Tin Wei Yuen, Clarissa Wei-Shuen Cheong, … Hui-Kim Yap, Kar-Hui Ng. Structured Re-training to Reduce Peritonitis in a Pediatric Peritoneal Dialysis Program: A Quality Improvement Intervention. Paediatric Nephrology, 2021, in press

2025/05/27
1E Kent Ridge Road, NUHS Tower Block, Singapore 119228
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