Professor Lee obtained her medical degrees from the National University of Singapore and the Royal College of Physicians, United Kingdom, and completed a fellowship in cancer genetics at Johns Hopkins School of Medicine, USA. She was Head of the Department of Haematology-Oncology at the National University Cancer Institute, Singapore (NCIS). She is currently Senior Consultant and Associate Director of Research at NCIS and Professor and Senior Principal Investigator at the Cancer Science Institute, National University of Singapore. She is ex-Chairperson of the Chapter of Medical Oncologists, Academy of Medicine, Singapore, and was a member of the Singapore Ministry of Health Specialist Accreditation Board for Medical Oncology.
She specializes in breast cancer and directs the Cancer Genetics Program at NCIS. Prof Lee is a clinician scientist and has been awarded the National Medical Research Council Singapore (NMRC) Senior Clinician Scientist Award three times. She is also Distinguished Senior Clinician awardee by the Singapore Ministry of Health. Her research interests are in developing novel therapeutics and predictive biomarkers in breast cancer and pharmacogenetics. She sits on drug advisory boards for breast cancer drugs for multiple international pharmaceutical companies and is a Steering Committee member of several international phase III randomized trials evaluating novel therapeutic approaches in breast cancer.
Prof Lee directs the Haematology-Oncology Research Group (HORG), a cancer clinical trials unit that supports ~200 phase I-III therapeutics clinical trials in solid tumors and haematological malignancies at NCIS. She has more than 260 peer-reviewed scientific publications, including publications in high impact journals such as Journal of Clinical Oncology, Annals of Oncology, British Journal of Cancer, Breast Cancer Research and Treatment, New England Journal of Medicine, Nature Genetics and Nature Medicine.