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Dr Lee Shir Ying

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  • Senior Consultant, Division of Haematology, Department of Haematology-Oncology, National University Cancer Institute, Singapore
  • Senior Consultant, Department of Laboratory Medicine, National University Hospital
  • Senior Consultant, Department of Haematology, Ng Teng Fong General Hospital
  • Senior Consultant, FAST Programme (Get Better), Alexandra Hospital
  • Senior Consultant, Chronic Programme (Live Better), Alexandra Hospital
  • Assistant Professor, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore


MBBS (S'pore), MRCP (UK), FRCPath (UK)



Clinical Disciplines/Programmes:

Chronic Programme (Live Better), FAST Programme (Get Better), Laboratory Medicine

Special Interests:

Anaemia and red cell disorders, Diagnostic haematology, Flow cytometry in haematologic and bone marrow diseases, Transfusion medicine, Thrombotic disorders


Dr Lee Shir Ying is a senior consultant haematologist at the Division of Haematology, Department of Haematology-Oncology, NCIS and Department of Laboratory Medicine, NUH. After receiving her undergraduate medical degree from the National University of Singapore in 2002, she trained in internal medicine and obtained her membership to the Royal College of Physicians of the United Kingdom in 2006. She undertook her specialty training in haematology under the Joint Commission of Specialist Training Singapore. In 2012, she obtained fellowship of the Royal College of Pathologist of the United Kingdom.

She is currently a teaching core faculty with the National University Health System Haematology Fellowship Programme and Assistant Professor in the Department of Medicine of the Yong Loo Lin School of Medicine. She also leads the Patient Blood Management subcommittee of NUH. Her clinical and research interests are in anaemia and red cell disorders, venous thrombosis, transfusion medicine, and diagnostic haematology including flow cytometry.

Journals & Publications

  1. 1. Lee SY, Teo WZY, Lim CXQ, Lee CT, Jen WY, de Mel S, Yap ES, Chee YL. Venous thromboembolism in an Asian COVID-19 cohort across 3 infection waves-a retrospective observational study. Res Pract Thromb Haemost. 2023 Oct 11;7(7):102218.
  2. Lee SY, Chen CME, Lim EYP, Shen L, Sathe A, Singh A, Sauer J, Taghipour K, Yip CYC. Image Analysis Using Machine Learning for Automated Detection of Hemoglobin H Inclusions in Blood Smears - A Method for Morphologic Detection of Rare Cells. J Pathol Inform. 2021 Apr 7;12:18.
  3. Lee SY, SS Hue. Terminal deoxynucleotidyl transferase negative B-lymphoblastic leukaemia/lymphoma with CD138 expression. Pathology. 2020;52(2):286-289
  4. Lee SY, Yap ES, Lee EY, Goh JH, Liu TC, Yip C. Evaluation of Thalassaemia Screening Tests in the Antenatal and Non-Antenatal Populations in Singapore. Ann Acad Med Singap. 2019 Jan;48(1):5-15.
  5. Lee SY, et al. Co-inheritance of High Oxygen Affinity Hemoglobin Helsinki [HBB:c.248A>T; β82(EF6)Lys→Met] with Hemoglobin H Disease. Hemoglobin. 2017;41(3):209-212
  6. Yip CYC, Yap ES, De Mel S, Teo WZY, Lee CT, Kan S, Lee MCC, Loh WNH, Lim EL, Lee SY. Temporal changes in immune blood cell parameters in COVID-19 infection and recovery from severe infection. Br J Haematol. 2020 Jul;190(1):33-36.
  7. Chan SSW, Lee SY. Acute Megakaryocytic Leukemia arising from Megakaryocyte/Erythroid Progenitor (MEP)-like cell. Int J Lab Hematol. 2022 Oct;44(5):808-811. doi: 10.1111/ijlh.13819.
  8. Ling VWT, Fan BE, Lau SL, Lee XH, Tan CW, Lee SY. Severe Thrombocytopenia, Thrombosis and Anti-PF4 Antibody after Pfizer-BioNTech COVID-19 mRNA Vaccine Booster-Is It Vaccine-Induced Immune Thrombotic Thrombocytopenia? Vaccines (Basel). 2022 Nov 26;10(12):2023.
  9. Lam JCM, Lee SY, Koh PL, Fong SZ, Abdul-Kadir NI, Lim CY, Zhang X, Bhattacharyya R, Soh SY, Chan MY, Tan AM, Kuperan P, Ang AL. Clinical and health-related quality of life outcomes of transfusion-dependent thalassaemia patients in Singapore. Blood Cells Mol Dis. 2021 May;88: 102547 

Professional Memberships

  • Member, Royal College of Pathologists, UK
  • Member, Royal College of Physicians, UK
  • Member, Singapore Society of Haematology

1E Kent Ridge Road, NUHS Tower Block, Singapore 119228
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National University Health System
  • National University Hospital
  • Ng Teng Fong General Hospital
  • Alexandra Hospital
  • Jurong Community Hospital
  • National University Polyclinics
  • Jurong Medical Centre
  • National University Cancer Institute, Singapore
  • National University Heart Centre, Singapore
  • National University Centre for Oral Health, Singapore
  • NUHS Diagnostics
  • NUHS Pharmacy
  • Yong Loo Lin School of Medicine
  • Faculty of Dentistry
  • Saw Swee Hock School of Public Health
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