Dr Lee Shing Fung is an Associate Consultant at the National University Cancer Institute, Singapore (NCIS), serving within the Department of Radiation Oncology. His work contributes to the provision of radiotherapy services across the NUHS and NHG clusters. He accomplished his medical training at the Li Ka Shing Faculty of Medicine, The University of Hong Kong (HKU) in 2010, followed by his appointment as a Fellow of the Royal College of Radiologists (UK) in 2015.
Dr Lee's clinical practice focuses on lymphoma, lower gastrointestinal tract cancers, central nervous system cancers, and gynaecological cancers. His research activities centre around enhancing the synergy of radiotherapy with systemic therapies, which includes traditional chemotherapy and newer targeted agents, particularly in managing gastrointestinal tract malignancies, lymphoma, and central nervous system cancers.
He is actively involved in large-scale data studies founded on population-based databases. Collaborating with Dr Miguel Fernandez from the London School of Hygiene and Medicine, UK, Dr Lee is currently investigating the causal inference of various agents on cancer risk and outcomes.
Parallel to these, Dr Lee holds a keen interest in the development of innovative techniques or regimens for radiotherapy delivery, as well as the assessment of radiation effects on normal tissues. His projects include evaluating the application of novel palliative radiotherapy dose-fractionation for advanced lung cancer patients and studying changes in physiological functions and blood counts following radiation therapy for lymphoma and gastrointestinal tract tumours.
Dr Lee has contributed to the scientific community by publishing numerous papers in esteemed peer-reviewed medical journals, adding to the understanding and management of various cancer types.
1. Lee, S. F., Yip, P. L., Chan, O. L., Lee, V. W. Y., Wong, A., & Choi, H. C. W. (2023). Brain Metastasis Growth Kinetics: A Novel Prognosticator for Stereotactic Radiotherapy.. Clinical oncology (Royal College of Radiologists (Great Britain)), 35(5), e328-e335. doi:10.1016/j.clon.2023.02.012
2. Behroozian, T., Goldshtein, D., Ryan Wolf, J., van den Hurk, C., Finkelstein, S., Lam, H., . . . Multinational Association of Supportive Care in Cancer (MASCC) Oncodermatology Study Group Radiation Dermatitis Guidelines Working Group. (2023). MASCC clinical practice guidelines for the prevention and management of acute radiation dermatitis: part 1) systematic review. . EClinicalMedicine, 58, 101886. doi:10.1016/j.eclinm.2023.101886
3. Behroozian, T., Bonomo, P., Patel, P., Kanee, L., Finkelstein, S., van den Hurk, C., . . . Multinational Association of Supportive Care in Cancer (MASCC) Oncodermatology Study Group Radiation Dermatitis Guidelines Working Group. (2023). Multinational Association of Supportive Care in Cancer (MASCC) clinical practice guidelines for the prevention and management of acute radiation dermatitis: international Delphi consensus-based recommendations.. The Lancet. Oncology, 24(4), e172-e185. doi:10.1016/s1470-2045(23)00067-0
4. Kwok, K. H. F., Ip, E. C., & Lee, S. F. (2023). The conundrums of the reasonable patient standard in English medical law.. BMC medical ethics, 24(1), 15. doi:10.1186/s12910-023-00892-2
5. Yip, P. L., Fung, W. H. B., Lee, F. A. S., Lee, C. F., Wong, N. S. M., & Lee, S. F. (2023). Effectiveness and safety of capecitabine, irinotecan and panitumumab in advanced colorectal cancer.. Frontiers in oncology, 13, 1138357. doi:10.3389/fonc.2023.1138357
6. Lee, S. F., Yip, P. L., Vellayappan, B. A., Chee, C. E., Wong, L. C., Wan, E. Y. -F., . . . Luque-Fernandez, M. A. (2022). Incident Cardiovascular Diseases Among Survivors of High-Risk Stage II-III Colorectal Cancer: A Cluster-Wide Cohort Study.. Journal of the National Comprehensive Cancer Network : JNCCN, 20(10), 1125-1133.e10. doi:10.6004/jnccn.2022.7042
7. Lee, S. F., Yip, P. L., Wong, A., Ng, F., Koh, V., Wong, L. C., . . . Mamon, H. J. (2022). Splenic irradiation contributes to grade ≥ 3 lymphopenia after adjuvant chemoradiation for stomach cancer.. Clinical and translational radiation oncology, 36, 83-90. doi:10.1016/j.ctro.2022.07.007
8. Lee, S. F., Vellayappan, B. A., Wong, L. C., Chiang, C. L., Chan, S. K., Wan, E. Y. -F., . . . Luque-Fernandez, M. A. (2022). Cardiovascular diseases among diffuse large B-cell lymphoma long-term survivors in Asia: a multistate model study.. ESMO open, 7(1), 100363. doi:10.1016/j.esmoop.2021.100363
9. Yip, P. L., Mok, K. C. J., Ho, H. S., Lee, W. Y. V., Wong, A. C. L., Lau, C. T., . . . Lee, S. F. (2022). Sensorineural Hearing Loss in Nasopharyngeal Carcinoma Survivors in the Modern Treatment Era - The Early and Late Effects of Radiation and Cisplatin.. Clinical oncology (Royal College of Radiologists (Great Britain)), 34(4), e160-e167. doi:10.1016/j.clon.2021.10.013
10. Yip, P. -L., Lee, S. -F., Choi, C. -W. H., Chan, P. -C. S., Cheung, K. -W. A., Chow, C. -H. J., . . . Tung, Y. S. (2021). External Validation of a Nomogram to Predict Survival and Benefit of Concurrent Chemoradiation for Stage II Nasopharyngeal Carcinoma. . Cancers, 13(17), 4286. doi:10.3390/cancers13174286
