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2024/03/11
Doctor Detail

Adj A/Prof Kuan Win Sen

Photo of Adj A/Prof Kuan Win Sen

Designations:

  • Senior Consultant, Emergency Medicine Department, National University Hospital
  • Senior Consultant, Emergency Medicine Department, Alexandra Hospital
  • Adjunct Associate Professor, Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore

Qualifications:

MBBS (Singapore), MRCS (A&E) Edin, MCI (NUS), FAMS

Specialties/Sub-specialties:

Emergency Medicine

Special Interests:

Emergency Critical Care, MedTech, Value-based Healthcare

Biosketch

Dr Kuan Win Sen is Senior Consultant and Research Director at the Emergency Medicine Department, National University Hospital, Core Faculty of the NUHS Emergency Medicine Residency Program, and Senior Consultant at the Urgent Care Centre, Alexandra Hospital. He concurrently holds the appointment of Adjunct Associate Professor in the Department of Surgery at the NUS Yong Loo Lin School of Medicine. He is also Research Officer at the Value Driven Office, Academic Informatics Office, NUHS, and is a member of the National Value-Based Healthcare Sepsis Clinician Workgroup and the Expert Group for the Agency for Care Effectiveness Clinical Guidance for Community-Acquired Pneumonia.

Dr Kuan is the department's clinical champion for sepsis, pneumonia, and pneumothorax. He was conferred the National Medical Excellence Team Award (2014) for outstanding contributions in improving hospital mortality rates and achieving significant cost savings for patients with severe community-acquired pneumonia. He was part of the team that won the Outstanding Poster Award for Value-Driven Care in Sepsis at the VDC Conference (2019) and the inaugural ICHOM–NEJM Catalyst Implementation Prize (2022) for sepsis outcomes work. In recognition of his research contributions, he has been conferred the NMRC Transition Award (2015), NMRC Clinician Innovator Development Award (2021), and NHIC Innovation to Startup (I2Start) Award (2024), the last supporting development of a field-deployable immune response profiling platform for sepsis. He also holds three patents reflecting his commitment to clinical innovation.

His research interests encompass sepsis, emergency critical care, MedTech, and value-based healthcare, with over 130 peer-reviewed publications to his name in high-impact journals including Annals of Emergency Medicine, European Heart Journal, European Journal of Heart Failure and Small. He maintains an h-index of 30 and is an active reviewer for more than 10 international journals. His education portfolio includes serving as a certified instructor for both the Advanced Cardiac Life Support and Advanced Trauma Life Support courses since 2008, regular facilitation at regional and local evidence-based medicine workshops. He has contributed to 19 chapters across leading emergency medicine textbooks.

Dr Kuan has fostered international collaborations through the Asia, Australia and New Zealand Dyspnoea in Emergency Departments (AANZDEM) Study Group, the Headache in Emergency Departments (HEAD) Study Group, and PREDICT-19 Consortium. He currently serves as Council Member of the College of Emergency Physicians and is a Fellow of the College of Clinician Scientists, Academy of Medicine, Singapore. He welcomes academic and commercial collaborations locally and internationally in emergency medicine and his areas of research interest.

Awards

  • 2024 - Gold Award at the NUH Incredible Care for Our Planet Award for Reduced Metered Dose Inhalers (ReMeDI): Preliminary Results from the Emergency Department (Team Leader)
  • 2024 - Certificate of Commendation – Medical Expert Report Writing for the Medical Expert Witness Training Course 2024
  • 2024 - Singapore Medical Journal Reviewer Recognition Awards 2023
  • 2023 - COVID-19 Resilience Medal
  • 2023 - The Commendation Medal (COVID-19)
  • 2022 - ICHOM-NEJM Catalyst Implementation Prize Winner 2022 for Sepsis VDO
  • 2020 - Singapore Medical Journal Reviewer Recognition Awards 2019

Journals & Publications

  1. Cheng L, Low SY, Boon Y, Goh C, Ng A, Ng AJY, Teo J, Johari NH, Pua YH, Chua MT, Kuan WS. Antimicrobial surface coating in the emergency department as protective technology for infection control (ASEPTIC): a pilot randomized controlled trial. Antimicrob Resist Infect Control. 2024 Oct 29;13(1):129. (IF 5.8)
  2. Yong LPX, Tung JYM, Lee ZY, Kuan WS, Chua MT†. Performance of Large Language Models in Patient Complaint Resolution: Web-Based Cross-Sectional Survey. J Med Internet Res. 2024 Aug 9;26:e56413. (IF 6.7) 
  3. See KC, Murphy D, Kumari S, Santoso E, Kuan WS. A Whole-of-Hospital Value-Driven Outcomes Approach to Optimize Clinical Outcomes and Minimize Hospitalization for Community-Acquired Sepsis. NEJM Catal Innov Care Deliv. 2023 July;4(7). (IF 3.3) 
  4. Zeming KK, Vernekar R, Chua MT, Quek KY, Sutton G, Krüger T, Kuan WS*, Han J*. Label-Free Biophysical Markers from Whole Blood Microfluidic Immune Profiling Reveal Severe Immune Response Signatures. Small. 2021 Mar;17(12):e2006123. (IF 12.463) 
  5. Kuan WS, Ibrahim I, Chan SP, Li Z, Liew OW, Frampton C, et al. Mid-regional pro-adrenomedullin outperforms N-terminal pro-B-type natriuretic peptide for the diagnosis of acute heart failure in the presence of atrial fibrillation. Eur J Heart Fail. 2020 Apr;22(4):692-700. (IF 12.768) 
  6. Wang J, Leong MC, Leong EZ, Kuan WS*, Leong DT*. Clinically relevant detection of Streptococcus pneumoniae with DNA-antibody nanostructures. Anal Chem. 2017 Jun 20;89(12):6900-6906. (IF 6.755) 
  7. Phua J, Dean NC, Guo Q, Kuan WS, Lim HF, Lim TK. Severe community-acquired pneumonia: timely management measures in the first 24 hours. Crit Care. 2016 Aug 28;20(1):237. (IF 9.372) 
  8. Kuan WS, Ibrahim I, Leong BS, Jain S, Lu Q, Cheung YB, Mahadevan M. Emergency Department Management of Sepsis Patients: A Randomized, Goal-Oriented, Noninvasive Sepsis Trial. Ann Emerg Med. 2016 Mar;67(3):367-378.e3. (IF 6.107) 
  9. Giovanni M, Setyawati MI, Tay CY, Hang Q, Kuan WS*, Leong DT*. Electrochemical Quantification of Escherichia coli with DNA Nanostructure. Adv Funct Mater. 2015 Jul;25(25):3840-3846. (IF 18.125) 
  10. Lim HF, Phua J, Mukhopadhay A, Ngerng WJ, Chew MY, Sim TB, Kuan WS, Mahadevan M, Lim TK. IDSA/ATS minor criteria aided pre-ICU resuscitation in severe community-acquired pneumonia. Eur Resp J. 2014 Mar;43(3):852-62. (IF 15.583)

Professional Memberships

  • Fellow, College of Emergency Physicians, Academy of Medicine, Singapore
  • Fellow, College of Clinician Scientists, Academy of Medicine, Singapore
  • Royal College of Surgeons of Edinburgh, United Kingdom
  • Singapore Medical Association

2026/05/07
1E Kent Ridge Road, NUHS Tower Block, Singapore 119228
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