Patient Care
Find a Doctor

Doctor Details

2024/03/11
Doctor Detail

Adj Prof Koh Liang Piu

Photo of Adj Prof Koh Liang Piu

Designations:

  • Senior Consultant, Division of Haematology, Department of Haematology-Oncology, National University Cancer Institute, Singapore
  • Adjunct Professor, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore

Qualifications:

MBBS (S'pore), MRCP

Specialties/Sub-specialties:

Haematology

Special Interests:

Leukaemia & Myeloid Disorder (MDS, MPD), Bone Marrow Transplant

Find Out More:

Biosketch

Dr Koh Liang Piu is an Adjunct Professor at the Department of Medicine, National University of Singapore Yong Loo Lin School of Medicine. He is also a senior consultant at the Department of Haematology-Oncology in the National University Cancer Institute, Singapore (NCIS). 

His research interest is predominantly focused on the use of alternative donor transplant such as haploidentical and umbilical cord blood transplantation. He is the leading investigator on the use ex-vivo T-cell depleted haploidentical transplant for adult patients with haematological malignancies and bone marrow failure syndromes.

Adj Prof Koh is the clinical director of the NCIS Adult Haematopoeitic Cell Transplant (HCT) programme at NCIS. Under his leadership, the NCIS Adult HCT programme has expanded and strengthened over the last 15 years, with notable developments such as expansion of the umbilical cord blood and haploidentical transplant programme, bringing the transplant outcome to levels comparable with the European and North American transplant centres. To date, he has performed more than 500 transplant for various haematological diseases.

Adj Prof Koh is also the principal investigator of several international, multi-centre phase II/III clinical trials in the treatment of  haematological malignancies, transplant-related infectious complications, studies on the use of umbilical cord transplant, alternative donor transplant, graft-versus-host disease (GVHD) treatment and prophylaxis, and novel approach in transplant conditioning regimens.  He has published more than 70 peer reviewed papers and 3 book chapters on the topic of HCT, and has also presented more than 30 abstracts in international haematology/HCT meetings. He also serves as a reviewer for some of international peer reviewed transplantation or haematology journals such as Blood, Blood Advances, Transplantation, Leukemia and Lymphoma.

Journals & Publications

  1. Koh LP, Linn YC, Boo YL, et al. Upfront memory T cell add-back with haploidentical TCRαβ-depleted graft in adults with haematological malignancies: a nationwide, multicentre, single-arm, prospective study. Bone Marrow Transplant. 2026;61(1):26-35.
  2. Horwitz ME, Stiff PJ, Cutler C, et al. (including Koh LP). Omidubicel vs standard myeloablative umbilical cord blood transplantation: results of a phase 3 randomized study. Blood. 2021;138(16):1429-1440.
  3. Maertens J, Rahav G, Lee DG, et al. (including Koh LP). Posaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trial. Lancet. 2021;397(10292):499-509.
  4. Boo YL, Koh LP. Hematopoietic Stem Cell Transplantation in T Cell and Natural Killer Cell Lymphomas: Update on Recent Advances. Transplant Cell Ther. 2021;27(5):355-366. (Epub 2021 Apr 20).
  5. Horwitz ME, Wease S, Blackwell B, et al. (including Koh LP). Phase I/II Study of Stem-Cell Transplantation Using a Single Cord Blood Unit Expanded Ex Vivo With Nicotinamide. J Clin Oncol. 2019;37(5):367-374.
  6. Marr KA, Schlamm HT, Herbrecht R, et al. (including Koh LP). Combination Antifungal Therapy for Treatment of Invasive Aspergillosis: A Randomized, Controlled Trial. Ann Intern Med. 2015;162(2):81-89.
  7. Koh LP, Chen CS, Tai BC, et al. Impact of Postgrafting Immunosuppressive Regimens on Nonrelapse Mortality and Survival after Nonmyeloablative Allogeneic Haematopoietic Stem Cell Transplant. Biol Blood Marrow Transplant. 2007;13(7):790-805.
  8. Koh LP, Rizzieri DA, Chao NJ. Allogeneic hematopoietic stem cell transplant using mismatched/haploidentical donors. Biol Blood Marrow Transplant. 2007;13(11):1249-1267.
  9. Rizzieri DA, Koh LP, Long GD, et al. Partially Matched, Nonmyeloablative Allogeneic Transplantation: Clinical Outcomes and Immune Reconstitution. J Clin Oncol. 2007;25(6):690-697.
  10. Koh LP, Chao NJ. Haploidentical hematopoietic cell transplantation. Bone Marrow Transplant. 2008;42(Suppl 1):S60-S63.
  11. Koh LP, Chao NJ. Nonmyeloablative allogeneic hematopoietic stem cell transplant using mismatched/haploidentical donors: A review. Blood Cells Mol Dis. 2008;40(1):20-24.

2026/02/09
1E Kent Ridge Road, NUHS Tower Block, Singapore 119228
Last updated on
Best viewed with Chrome 79.0, Edge 112.0, Firefox 61.0, Safari 11
National University Health System
  • National University Hospital
  • Ng Teng Fong General Hospital
  • Alexandra Hospital
  • Tengah General and Community Hospital
  • Jurong Community Hospital
  • National University Polyclinics
  • Jurong Medical Centre
  • National University Cancer Institute, Singapore
  • National University Heart Centre, Singapore
  • National University Centre for Oral Health, Singapore
  • NUHS Diagnostics
  • NUHS Pharmacy
  • NUHS Regional Health System Office
  • NUS Yong Loo Lin School of Medicine
  • NUS Faculty of Dentistry
  • NUS Saw Swee Hock School of Public Health
Back to Top