Dec 2011
NUS-JSPS (Bilateral Exchange Program) Joint Seminar 2012
| S/N |
Project Title |
PI |
Department |
| 1 |
Bridging Basic Science with Translational Infectious Disease Research |
Chow Tak Kwong, Vincent |
Microbiology |
NUS Cross Faculty Grant call in Sep 2011
| S/N |
Project Title |
PI |
Department |
| 1 |
Peptide-assisted delivery of DNA minimal vectors for RNAi-based knockdown of target genes |
Volker Patzel |
Microbiology |
| 2 |
Improving depressive symptoms in community-dwelling older Malay Singaporean adults using life story review: a randomized controlled trial |
Chan Moon Fai |
ALCNS |
| 3 |
Development of a peptide-based vaccine against Enterovirus 71 using core-shell nanoparticles as vaccine delivery system |
Alonso, Sylvie |
Microbiology |
| 4 |
Development Of An Innovative Anastomotic Device Prototype For Surgical Treatment Of Prostate Cancer |
Chiong, Edmund |
Surgery |
NMRC Individual Research Grant call in May 2011
| S/N |
Project Title |
PI |
Department |
| 1 |
Functional genome-wide analysis Of host And viral factors In mediating the clinical pathogenesis of human enterovirus 71 Infection: An implication for biomarker(s) discovery. |
Chu Jang Han |
Microbiology |
| 2 |
Translating drug-Induced cell death into novel anti-malarial strategies. |
Tan Shyong Wei, Kevin |
Microbiology |
| 3 |
An investigation into the immunomodulatory properties of Blomia tropicalis and the development of a better asthma model. |
Kemeny, David Michael |
Microbiology |
| 4 |
Circadian disruption in prostate cancer. |
H. Phillip Koeffler |
Medicine |
| 5 |
Paired pre and post treatment whole genome gene expression profiling of bone marrow as a diagnostic and novel prognostic tool for treatment of childhood acute lymphoblastic and myeloid leukaemias – a Malaysia-Singapore study proposal. |
Yeoh Eng Juh |
Paediatrics |
| 6 |
Project to explore the potential role of diosgenin to overcome chemoresistance in prostate cancer through modulation of multiple pro-inflammatory signaling cascades. |
Gautam Sethi |
Pharmacology |
| 7 |
Elucidating the mechanistic role of lipid and protein metabolism on the pathophysiology of insulin resistance towards nutritional intervention to prevent Type 2 diabetes mellitus. |
Khoo Chin Meng |
Medicine |
NRF Proof of concept Grant call in May 2011
| S/N |
Project Title |
PI |
Department |
| 1 |
Development of a ‘wound dressing patch’ made up of an aloe-vera-nanomesh impregnated with human umbilical cord Wharton’s jelly stem cells or its extracts for keloid suppression and wound healing. |
Fong Chui Yee |
Obstetrics & Gynaecology |
| 2 |
A novel multiple-zone soft contact lens to slow myopia progression. |
Saw Seang Mei |
School of Public Health |
November 2011
DSTA DIRP grant call in Jun 2011
| S/N |
Project Title |
PI |
Department |
| 1 |
New generation recombinant human interferon: Broad spectrum prophylactic and antiviral countermeasure for emerging infectious disease. |
Chu Jang Han |
Microbiology |
| 2 |
Project to explore the potential role of novel inhibitors of transcription factor NF-κB in radioprotection during radiation exposure. |
Gautam Sethi |
Pharmacology |
NMRC Exploratory/Developmental Grant call in May 2011
| S/N |
Project Title |
PI |
Department |
| 1 |
Role of cathepsins in pathogensis of Burkholderia pseudomallei infection. |
Gan Yunn hwen |
Biochemistry |
| 2 |
Elucidating the genetic and clinical heterogeneity of neuromuscular disorders (NMDs). |
Lai Poh San |
Paediatrics |
| 3 |
Comparative evaluation of the bacterial gene composition of stool microbiota in infants with and without eczema |
Lee Bee Wah |
Paediatrics |
| 4 |
CARE- Cord-stem cell Application for Regeneration Enhancement |
Chang Kin Yong |
Surgery |
NMRC New Investigator Grant call in May 2011
| S/N |
Project Title |
PI |
Department |
| 1 |
Emergency Department management of sepsis patients: A Goal-Oriented Non-Invasive Sepsis Trial (AGONIST) |
Kuan Win Sen |
Emergency |
| 2 |
HIV-Associated Osteoporosis in Singapore: Prevalence and Risk Factors |
Chew Sern Yan Nicholas |
Medicine |
| 3 |
TLR-3 ligand as an immune adjuvant in cetuximab based therapy in Head and Neck Cancer |
Lim Chwee Ming |
Otolaryngology |
|
August 2011
MOE Academic Research Fund Tier 1 FRC Call in Jan 2011
| S/N |
Project Title |
PI |
Department |
| 1 |
Regulation of apoptosis by TERT on Bax and other Bcl-2 family members |
Wang Xueying |
Biochemistry |
| 2 |
Whole genome location analysis of CARM1 and CARM1-mediated histone H3 arginine 17 methylation in embryonic stem cells |
Wu Qiang |
Biochemistry |
| 3 |
Exploration of the potential of endothelial progenitor cells (EPCs) in pathogenesis and as a biomarker in concomitant atherogenesis and bone loss in systemic lupus erythematosus |
Anselm Mak |
Medicine |
| 4 |
Therapeutic attenuation of liver injury in animal model of liver failure |
Dan Yock Young |
Medicine |
| 5 |
Project to explore the potential role of novel series of synthetic pyrrolizidines in the prevention and treatment of hepatocellular carcinoma |
Gautam Sethi |
Pharmacology |
July 2011
Singapore Millennium Foundation in Jan 2011
| S/N |
Project Title |
PI |
Department |
| 1 |
Tele-Rehabilitation for Newly-Disabled Homebound Older Persons Needing Supervised Physical Therapy |
Koh Choon Huat Gerald
|
Epidemiology and Public Health |
SMART Innovation Grant Call in Mar 2011
| S/N |
Project Title |
PI |
Department |
| 1 |
Partially biodegradable percutaneous caval valve implantation for severe tricuspid regurgitation |
Tay Lik Wui Edgar |
Medicine |
| 2 |
Three- dimensional compass navigation tool to augment laparo-endoscopy |
Lee Tswen Wen Victor |
Surgery |
NUHS Clinician Research Grant
| S/N |
Project Title |
PI |
Department |
| 1 |
Polycaprolactone (PCL) and PCL-Tri Calcium Phosphate (TCP) scaffold Astrocyte Response and Lesion Growth in Acute Traumatic Brain Injury |
David Choy Kim Seng |
Surgery |
| 2 |
Identification of the aberrant Leukaemic stem cell phenotype for disease monitoring and potential therapeutic targeting |
Lee Shir Ying |
Haematology - Oncology |
| 3 |
Viral Mediators of HIV-Associated Osteoporosis |
Nicholas Chew Sern Yan |
Medicine |
| 4 |
Exploration of plasma microparticles (PMPs) as mediators and biomarkers of disease activity in systemic lupus erythematosus (SLE) |
Aisha Lateef |
Medicine |
| 5 |
Emergency Department management of sepsis patients: A Goal-Oriented Non-Invasive Sepsis Trial (AGONIST) |
Kuan Win Sen |
Emergency Medicine |
| 6 |
An Eye into the Heart - retinal vascular changes in Kawasaki syndrome as a marker of coronary artery disease |
Terence Lim Chee Wen |
Paediatrics |
| 7 |
Clinical relevance of PRL3, p53 and MDM2 expression in AML |
Chng Wee Joo |
Haematology - Oncology |
| 8 |
Strain characterization of NDM-1 containing Enterobacteriaceae in Singapore |
Michelle Balm |
Laboratory Medicine |
| 9 |
Aminoguanidine: A Prospective Medicine for Periodontal Treatment |
Chang Po-Chun |
Preventive Dentistry |
|
June 2011
NUS-Mindef JPP July 2010 Grant Call
| S/N |
Project Title |
PI |
Department |
| 1 |
Testing the use of oral N-acetylcysteine to enhance antibiotic treatment efficacy for exposure to Burkholderia pseudomallei in animal models |
Gan Yunn Hwen |
Biochemistry |
|
May 2011
NMRC Nov 2010 Grant Call (IRG)
| S/N |
Project Title |
PI |
Department |
| 1 |
A novel isoform of human Mixed Lineage Leukemia 5 (MLL5) in the development of HPV16/18-associated cervical cancer: a potential new diagnostic marker and therapeutic target |
Deng Lih Wen |
Biochemistry |
| 2 |
Pathophysiology of HbeAg negative chronic hepatitis B |
Lim Seng Gee |
Medicine |
| 3 |
Guillain-Barré syndrome in Singapore:
Electrophysiological subtypes and immunopathological features |
Nobuhiro Yuki |
Microbiology |
| 4 |
Regulation of innate and adaptive immune responses to H1N1 and H3N2 influenza viral infection by MAPK phosphatases |
Zhang Yongliang |
Microbiology |
| 5 |
Detection of minimal residual disease in acute myeloid leukemia |
Dario Campana |
Paediatrics |
| 6 |
The effects of steroid therapy on satellite cells and fibro-adipocytes in Duchenne and Becker Muscular Dystrophy |
Stacey Tay Kiat Hong |
Paediatrics |
| 7 |
Does relaxin-3 relax the brain? An investigation of the nucleus incertus and relaxin-3 as novel targets for the treatment of anxiety disorders |
Gavin S. Dawe |
Pharmacology |
| 8 |
CHInese Medicine Neuroaid Efficacy on Stroke Recovery (CHIMES) Study |
Christopher Chen Li Hsian |
Pharmacology |
| 9 |
Investigation of the tumor suppressor functions of Sema5A and plexin-B3 in human gliomas |
Alan Lee Yiu Wah |
Physiology |
| 10 |
To Investigate The Effectiveness Of Zinc Supplementation In Patients With Advanced Non Small Cell Lung Cancer Treated With Palliative Radiotherapy; Can Lipid Oxidation Products Be Used To Predict Which Patients Will Benefit? |
Keith Lim Hsiu Chin |
Radiation Oncology |
NMRC Nov 2010 Grant Call (EDG)
| S/N |
Project Title |
PI |
Department |
| 1 |
Analysis of novel genes in microglia and their implications in neurodegenerative diseases |
S. Thameem Dheen |
Anatomy |
| 2 |
Does polyphenol supplementation improve vascular function? A cross-over study incorporating markers of oxidative damage, endothelial and platelet function |
Raymond Seet Chee Seong |
Medicine |
| 3 |
Cell Death Index as a novel, rapid and valuable tool for classification of antimalarial drug action |
Kevin Tan Shyong Wei |
Microbiology |
| 4 |
Monoclonal atibody targeting of nuclear autoantigens to specific antigen-presenting cells: Investigation of autoantibody induction |
Lu Jinhua |
Microbiology |
| 5 |
An assessment of gastric mucosal IL-22 expressing cells in intestinal metaplasia associated |
Justin Wong Soon Boon |
Microbiology |
| 6 |
Investigation of the role of serum amyloid A in atherosclerosis through initiation of apotosis |
Heng Chew Kiat |
Paediatrics |
| 7 |
Exploiting the relationship between parkin and DMT1 to generate a novel 'gene-environemental' mouse model of Parkinson's disease |
Lim Kah Leong |
Physiology |
NMRC Nov 2010 Grant Call (NIG)
| S/N |
Project Title |
PI |
Department |
| 1 |
The effectiveness of therapeutic play intervention on outcomes of children undergoing inpatient elective surgeries: a randomised control trial |
He Hong Gu |
Alice Lee Centre for Nursing Studies |
| 2 |
The role of adipose tissues expandability in maintaing metabolic homeostatsis |
Sue-Anne Toh Ee Shiow |
Medicine |
| 3 |
Feasibility study of polarimetry imaging for the diagnosis of gastric pathologies including pre-neoplasia and neoplasia |
Lim Lee Guan |
Medicine |
| 4 |
Glycemic and non-glycemic determinants of HbA1C and the identification of novel markers of glycemia |
Kao Shih Ling |
Medicine |
| 5 |
In-silico design of trans-splicing RNA and amalgamation with other RNA technologies for genetic therapy |
Volker Patzel |
Microbiology |
| 6 |
Is it safe to transfuse leucocyte depletion filer (LDF) processed Intra-Operative Cell Salvage (IOCS) blood in spine tumor surgery |
Naresh Satyanarayan Kumar |
Orthopaedics Surgery |
VISA Research Grant (July 2010 Grant Call)
| S/N |
Project Title |
PI |
Department |
| 1 |
The effect of Tai Chi standing postures on improving walking stability and cognitive states in the rehabilitation of the elderly. A biomechanical study |
Barry P Pereira |
Orthopaedics Surgery |
National Kidney Foundation
| S/N |
Project Title |
PI |
Department |
| 1 |
Augmentation of glutathione levels through oral N-acetylcysteine supplementation in Type 2 diabetic patients to increase resistance to bacterial infection |
Gan Yunn Hwen |
Biochemistry |
| 2 |
Reducing nephrotoxicity of vancomycin: A prospective, randomised study of continuous versus intermittent infusion of vancomycin |
Jolene Oon |
Medicine |
| 3 |
The origin of anti-C1q autoantibodies - a key nephritogenic factor for proliferative lupus nephritis |
Lu Jinhua |
Microbiology |
| 4 |
Activation of Na+/K+-ATPase with a rat derived DR region specific antibody-A new approach to treat renal ischemic diseases |
Bian Jinsong |
Pharmacology |
| 5 |
Functional analysis of human miR-196a in human renal cell carcinoma |
Lina Lim Hsiu Kim |
Physiology |
SERC Biomedical Engineering Proposal
| S/N |
Project Title |
PI |
Department |
| 1 |
Percutaneous mitral valve replacement |
Jimmy Hon |
CTVS |
| 2 |
Standardized Electronic Assay for Enumeration of Circulating Tumor Cells using CMOS Technology |
Ross Soo |
Haematology-Oncology |
| 3 |
A culture-free and PCR-free technique for rapid detection of bacteria from pathological samples |
Dale Fisher |
Medicine |
| 4 |
Development of an Infection-resistant Urinary Catheter Coated by Short Antimicrobial Peptides |
Paul A Tambyah |
Medicine |
| 5 |
Generation of platelet-rich Plasma by ultrasound standing waves |
Casey Chan |
Orthopaedic Surgery |
| 6 |
Silk sleeve device for improving the graft bonding at the bone tunnel |
James Hui Hoi Po |
Orthopaedic Surgery |
| 7 |
A novel hybrid multi-material micro-dispensing system to develop 3-dimensional tissue engineered meniscal implants and osteochondral grafts |
Wilson Wang Ee Jen |
Orthopaedic Surgery |
| 8 |
Development of Novel Yolk-Shell Nanoparticle Based Moldable Putty for Surgery |
Wong Hee Kit |
Orthopaedic Surgery |
| 9 |
Office-based Ventilation Tube Applicator for Patients with Otitis Media with Effusion |
Lynne Lim Hsueh Yee |
Otolaryngology |
|
Mar 2011
DSO-NUS Research Grant
| S/N |
Project Title |
PI |
Department |
| 1 |
Assessment of Bio-Toxin by OIA |
P. Gopalakrishnakone |
Anatomy |
A*STAR Bench and Bedside Grant
| S/N |
Project Title |
PI |
Department |
| 1 |
Novel diagnostics and Preemptive Therapeutic Approaches to Intestinal Metaplasias, the Precursors of Gastric and Esophageal Adenocarcinoma |
Ho Khek Yu |
Medicine |
Clinician Scientist Award
| S/N |
Project Title |
PI |
Department |
| 1 |
Predicting outcomes in acute coronary syndrome: a translational approach integrating population-specific clinical risk models, platelet reactivity and metabolomic biomarkers |
Mark Chan |
NUHCS - Cardiac |
| 2 |
Adjunctive vitamin D3 with anti-fungal agents as novel drug combinations for ehanced treatment of invasive fungal infrections |
Louis Chai |
Medicine |
| 3 |
Novel anti-adrogens of botanical origin as multiple site modulators of androgen receptor signalling to inhibit prostate cancer development and growth development and growth |
Yong Eu Leong |
Obstetrics & Gynaecology |
Singapore Immunology Network
| S/N |
Project Title |
PI |
Department |
| 1 |
A study of the clinical and molecular aspects of mild crustacean shellfish allergy and the role of dust mite allergen cross reactivity - A novel inhalant-food allergy syndrome |
Lee Bee Wah |
Paediatrics |
| 2 |
Investigating the immune mechanisms which regulate soluble urokinase plasminogen activator receptor (sUPAR) production crucial for disease progression in immune-mediated focal |
Yap Hui Kim |
Paediatrics |
| 3 |
Characterization of atopy-related IgE-signalling pathways by a functional genomics approach |
Wang De Yun |
Otolaryngology |
| 4 |
Establishment of primary human nasal epithelial stem/progenitor cells in an air-liquid interface culture model and identification of their roles in infectious and allergic diseases of the upper airway |
Wang De Yun |
Otolaryngology |
| 5 |
Immune Signatures and Biomarker Profiling of Frailty |
Ng Tze Pin |
Psychological Medicine |
|
Feb 2011
MOH Health Services Research Grant
| S/N |
Project Title |
PI |
Department |
| 1 |
Evidence Based Postoperative Monitoring Stratification Protocol - Use of the Surgical Risk Score (SRS) to Enhance Monitoring Capabilities |
Raymond Goy |
Anaesthesia |
| 2 |
The health, social and financial effects of care-giving among primary caregivers of elderly stroke patients in the first post stroke year: a prospective cohort study |
Gerald Koh Choon Huat |
EPH |
| 3 |
Developing and testing the new, 5-level EQ-5D questionnaire for health services research in Singapore |
Luo Nan |
EPH |
| 4 |
Colonoscopy Quality and Safety in Public Hospitals in Singapore |
Yeoh Khay Guan |
Medicine |
MOE Academic Research Fund Tier 2
| S/N |
Project Title |
PI |
Department |
| 1 |
Understanding sarcopenia using a C.elegans model |
Barry Haliwell |
Biochemistry |
|
Jan 2011
NUS Cross-Faculty Research Grant
| S/N |
Project Title |
PI |
Department |
| 1 |
Investigation of the effects of sound waves on cell growth |
Chen Ee Sin |
Biochemistry |
| 2 |
Tele-Rehabilitative Technologies for Home Therapy in Stroke Patients |
Gerald Koh Choon Huat |
EPH |
| 3 |
Novel Chemical Modifications of Andrographolide for Anti-Inflammatory Drug Screening |
Wong Wai Shiu, Fred |
Pharmacology |
|
